Discovery of a pyrano[2,3-b]pyridine derivative yx-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis

HIGHLIGHTS

• who: Tao Liu from the College of Pharmacy, Third Military Medical University, Chongqing, China have published the paper: Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis, in the Journal: (JOURNAL)
• what: This study evaluated the effects of YX-2102 on the early inflammatory stage (day 7) of BLM-induced PF. This study investigated whether YX-2102 can inhibit the EMT process. Consistently, using YX-2102, a novel selective CB2R agonist, the authors show that CB2R activation protects against BLM-induced lung fibrosis . . .
  

   

  

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