HIGHLIGHTS
- who: Karthiga Santhana Kumar from the Childrenu2019s Research Center, University Childrenu2019s Hospital Zu00fcrich, Switzerland have published the article: Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth, in the Journal: (JOURNAL)
- what: The aim of this study was to identify a small molecule of FRS2 to interrupt oncogenic signal transmission from FGFRs. To conclude, the authors provide strong evidence that compound 7 interference with FRS2 functions, represses oncogenic FGFR signaling and invasiveness in human cancer cells and can reduce tumor growth in_vivo. The aim of this study was to specifically . . .
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