HIGHLIGHTS
- who: Julia Schanin from the , Industrial Rd Suite, San Carlos, CA, University have published the paper: Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells, in the Journal: (JOURNAL) of 23/06/2022
- what: The authors report the generation of a panel of Siglec-6-specific mAbs binding to a range of extracellular domains to investigate the influence of epitope specificity on MC inhibition via Siglec-6 agonism. To better understand Siglec-6 epitope-dependent agonism the authors focused on AK02 and AK04 because these clones bind to domain 1 . . .
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