Discovery of anti-pd-l1 human domain antibodies for cancer immunotherapy

HIGHLIGHTS

  • who: Hao Liu from the Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, Kansas Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO, United States have published the research: Discovery of Anti-PD-L1 Human Domain Antibodies for Cancer Immunotherapy, in the Journal: (JOURNAL)
  • how: A PD-1/PD-L1 blocking assay was developed to evaluate the blocking efficacy of these dAbs. Next the authors investigated whether CLV3 also block the mouse PD-1/PD-L1 interaction because the authors need to evaluate the antitumor activity of . . .

     

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