HIGHLIGHTS
- who: Yushan Qiu from the (UNIVERSITY) have published the Article: Discovery of Boolean metabolic networks: integer linear programming based approach, in the Journal: (JOURNAL)
- what: The authors propose a graph-based computational damage model that summarizes the impact of enzymes on compounds in metabolic networks. This works aim to identify the biological targets (could be enzyme or protein) for drugs which can be manipulated so as to produce the desired effect (i.e., curing a disease) with minimum disruptive side-effects . The authors develop an efficient method based on Integer_Linear_Programming which has a wide application . . .
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