Discovery of driver non-coding splice-site-creating mutations in cancer

HIGHLIGHTS

• who: Song Cao from the Washington University StLouis, MO, USA. have published the paper: Discovery of driver non-coding splice-site-creating mutations in cancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: Compared to previous studies16,18, this study focuses on the comprehensive discovery of nc-SCMs. The study demonstrates that 16% of tumors from various cancer types harbor non-coding mutations that create alternative splice sites based on TCGA WGS data, which is a higher figure than the 1% and 9% of tumors with nc-SCMs from the 2018 study16 and the Shiraishi . . .
  

   

  

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