Discovery of novel dihydrolipoamide s-succinyltransferase inhibitors based on fragment virtual screening

HIGHLIGHTS

  • who: Chengqian Wei and colleagues from the State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green have published the Article: Discovery of Novel Dihydrolipoamide S-Succinyltransferase Inhibitors Based on Fragment Virtual Screening, in the Journal: (JOURNAL) of 30/Nov/2021
  • what: The conconstruction process of this model based on DLST is shown in Figure 1. struction process of this model based on DLST is shown in Figure 1.
  • how: The six six fragments the result showed that most of the fragments had excellent bactericidal activity except the . . .

     

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