HIGHLIGHTS
- who: Elizaveta D. Gladkova and colleagues from the Department of Natural Sciences, Novosibirsk State University, Pirogova str1, Novosibirsk, Russia have published the Article: Discovery of Novel Sultone Fused Berberine Derivatives as Promising Tdp1 Inhibitors, in the Journal: Molecules 2021, 26, 1945. of 30/03/2021
- what: The aim of this study was to investigate the reactions of berberrubine with aliphatic sulfochlorides, identification of their main reaction pathways, and isolation and characterization of the reaction products.
- how: Since the synchronous process (mechanism C) involves sulfene 15b and to determine the possibility of this reaction . . .
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