Discovery, optimization and biodistribution of an affibody molecule for imaging of cd69

HIGHLIGHTS

  • who: Jonas Persson from the DepartmentUppsala University have published the paper: Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69, in the Journal: Scientific Reports Scientific Reports

SUMMARY

    One construct had an additional C-terminal cysteine, and in another, Z ­ CD69:2 was followed by a (­ G4S)3 linker and then an albumin binding domain (ABD) derived from streptococcal Protein G. Thus, the three expression products from these constructs were ­H6-ZCD69:#, ­H6-ZCD69:#-Cys and ­H6-ZCD69:#-(G4S)3-ABD. Sprague-Dawley rats (n=15 in total, n=3 . . .

     

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