Discs large 1 (dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (ap-1) in forming weibel-palade bodies of endothelial cells

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  • who: Monique Philippe from the (UNIVERSITY) have published the research work: Discs Large 1 (Dlg1) Scaffolding Protein Participates with Clathrin and Adaptator Protein Complex 1 (AP-1) in Forming Weibel-Palade Bodies of Endothelial Cells, in the Journal: (JOURNAL) of November/30,/2012
  • what: Instead, the authors show that Dlg1 is present in Triton X-100-insoluble, low-speed fractions of hCMEC/D3 lysates (i.e. large-size cytoskeleton fraction) and by confocal microscopy is visualized to colocalize with microtubules, intermediate filaments, and Golgi markers (Figs 2 and 4). The authors show that Dlg1 is . . .

     

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