Diseased, differentiated and difficult: strategies for improved engineering of in vitro neurological systems

HIGHLIGHTS

  • who: Lyandysha V. Zholudeva from the Columbia University, United States have published the Article: Diseased, differentiated and difficult: Strategies for improved engineering of in vitro neurological systems, in the Journal: (JOURNAL)
  • what: The authors propose that combining aspects of directed and induced differentiations could improve cell type specificity, purity, scalability, and modularity in downstream applications.

SUMMARY

    This process bypasses or drastically abbreviates developmental progression, and shortens the amount of time that it takes to generate neurons, with morphological changes occurring within 72 h in human cells and spontaneous electrical activity observable . . .

     

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