Disordered t cell-b cell interactions in autoantibody-positive inflammatory arthritis

HIGHLIGHTS

  • who: Amu00e9lie M. Julu00e9 from the University of Lisbon, Portugal Osaka University, Japan have published the article: Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis, in the Journal: (JOURNAL)
  • what: The authors show that Tph cells accumulate in the joints of oligo JIA patients and are enriched in the SF of children with autoantibodies (ANA + patients). The studies report on protein and gene concern that some Teff cells, and especially Tph cells, may have been accidently captured as Tregs in the sorting strategy that was used for the scRNA-seq studies and . . .

     

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