Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of plasmodium ovale curtisi and p. o. wallikeri in africa

HIGHLIGHTS

• who: Jing Chen and colleagues from the Editor:, University of the National Natural Science Foundation of China have published the article: Disparate selection of mutations in the dihydrofolate reductase gene (dhfr) of Plasmodium ovale curtisi and P. o. wallikeri in Africa, in the Journal: (JOURNAL)
• what: High frequencies of S58R and S113 N/T mutations were observed in podhfr in P. ovale curtisi isolates from Africa, and evidence of selective sweeps around these mutant loci were recorded.
• how: The authors analyzed genetic polymorphisms in P. ovale dhfr crt and cytb in 147 samples . . .
  

   

  

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