Display of the human mucinome with defined o-glycans by gene engineered cells

HIGHLIGHTS

• who: Rebecca Nason from the Departments University of have published the Article: Display of the human mucinome with defined O-glycans by gene engineered cells, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate the utility of the cell-based mucin display through probing and dissecting selective mucin TR binding specificities of microbial adhesins, and the power of making defined mucin TRs available through analysis of the substrate specificities of microbial glycopeptidases, as well as by demonstrating selective binding by an influenza virus.
• how: For direct intact mass analysis of mucin . . .
  

   

  

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