Disrupting the α7nachr-nr2a protein complex exerts antidepressant-like effects

HIGHLIGHTS

• who: Anlong Jiang from the (UNIVERSITY) have published the article: Disrupting the u03b17nAChR-NR2A protein complex exerts antidepressant-like effects, in the Journal: (JOURNAL)
• what: The authors report that disrupting the u03b17nAChR-NMDAR complex with the interfering peptide also has antidepressant-like effects in the forced swim test (FST) a common rat behaviour screening test for antidepressant effects.
• how: The authors used the FST to screen for antidepressant-like effects of the TAT-u03b17-peptide.
• future: Of course many additional experiments are required to understand the A B IP u03b17 nAChR . . .
  

   

  

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