HIGHLIGHTS
- who: Abdeldjalil Madani et al. from the Aix Marseille University and by the grant ANR- CE44, from the Agence Nationale de la have published the Article: Dissecting the antibacterial activity of oxadiazolone-core derivatives against Mycobacterium abscessus, in the Journal: PLOS ONE of December/18,/2019
- what: As already highlighted in the case of M. tuberculosis [12], our series of oxadiazolone-core OX derivatives are able to impair different metabolic pathways during either extracellular and/or intracellular bacterial growth via the inhibition of various (Ser/Cys)-based enzymes, therefore resulting in M. abscessus death.
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