Dissecting the dynamic transcriptional landscape of early t helper cell differentiation into th1, th2, and th1/2 hybrid cells

HIGHLIGHTS

  • who: Philipp Burt from the University of Washington, United States have published the research: Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells, in the Journal: (JOURNAL)
  • what: To further investigate the relation of Th1/2 hybrid cells to Th1 and Th2 cells, the authors restricted the analysis to the set of Th1 vs. Th2 DEG, thereby focusing on genes that are highly related to differential Th-cell fate development . For the Th cell-specific gene sets, the authors focused on the transcription factors GATA . . .

     

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