Dissecting the effects of aldosterone and hypokalemia on the epithelial na channel and the nacl cotransporter

HIGHLIGHTS

  • who: Mathias Kristensen and colleagues from the Department of Biomedicine, Aarhus University, Aarhus, Denmark have published the research work: Dissecting the Effects of Aldosterone and Hypokalemia on the Epithelial Na Channel and the NaCl Cotransporter, in the Journal: (JOURNAL)
  • what: The major aim of this study was to dissect the isolated effects of aldosterone and hypokalemia on ENaC and NCC using a variety of in_vivo and ex vivo approaches (see Supplementary Figure S1 for experimental design). The authors show that both the abundances and cleavage of u03b1- and u03b3ENaC are increased directly by aldosterone in . . .

     

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