HIGHLIGHTS
- who: Annamaria Antona and colleagues from the Centre of Excellence in Aging Sciences, Department of Translational Medicine, University of Piemonte Department of Health Sciences, University of Piemonte Orientale, Novara, Italy have published the paper: Dissecting the Mechanism of Action of Spiperoneu2014A Candidate for Drug Repurposing for Colorectal Cancer, in the Journal: (JOURNAL) of 20/01/2022
- what: In this study, through in_vitro and omics analysis, the authors demonstrate that spiperone proves effective in killing CRC cells and CRC-SCs by disrupting intracellular Ca2+ kinetics and inducing ER stress, lipid metabolism dysregulation, and damage to the . . .
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