Dissecting the roles of the tuberin protein in the subcellular localization of the g2/m cyclin, cyclin b1

HIGHLIGHTS

  • who: Adam Pillon and colleagues from the Department of Biomedical Sciences, University of Windsor, Windsor, Ontario, Canada have published the research: Dissecting the roles of the Tuberin protein in the subcellular localization of the G2/M Cyclin, Cyclin B1, in the Journal: PLOS ONE of 26/Oct/2021
  • what: The authors demonstrate that exogenous expression of a fragment of the N-term region of Tuberin alters the subcellular localization of and increases cell proliferation. This work shows that imbalances in the levels of Tuberin mutants, including amplifications, can cause adverse consequences for cell biology. The . . .

     

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