Dissolving microneedles loaded with nanoparticle formulation of respiratory syncytial virus fusion protein virus-like particles (f-vlps) elicits cellular and humoral immune responses

HIGHLIGHTS

• who: Ipshita Menon et al. from the Center for Drug Delivery Research, Vaccine Nanotechnology Laboratory, College of Pharmacy, Mercer University, Atlanta, GA, USA have published the article: Dissolving Microneedles Loaded with Nanoparticle Formulation of Respiratory Syncytial Virus Fusion Protein Virus-like Particles (F-VLPs) Elicits Cellular and Humoral Immune Responses, in the Journal: Vaccines 2023, 11, 866. of 18/04/2023
• what: In this proof-of-concept study, the authors demonstrate how loading F-VLP nanoparticles along with adjuvant MPL-A nanoparticles into dissolving microneedles induces a robust humoral and cellular immune_response in_vivo.
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