Distant downstream sequence determinants can control n-tail translocation during protein insertion into the endoplasmic reticulum membrane*

HIGHLIGHTS

  • who: IngMarie Nilsson from the (UNIVERSITY) have published the Article: Distant Downstream Sequence Determinants Can Control N-tail Translocation during Protein Insertion into the Endoplasmic Reticulum Membrane*, in the Journal: (JOURNAL) of August/27,/1999
  • what: The authors have analyzed the insertion of the E. coli inner membrane protein ProW into ER-derived microsomal membranes.
  • how: N-tail translocation also became markedly more efficient in the *TM1-3/P2⬘ *TM1- 4/P2⬘ *TM1-5/P2⬘ *TM1- 6/P2⬘ and *TM1-7/P2⬘ constructs when the N-tail was shortened to 30 residues (Fig . . .

     

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