HIGHLIGHTS
- who: E. J. Brace et al. from the Department of Developmental Biology, Washington University School of Medicine, StLouis, Missouri have published the Article: Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity, in the Journal: (JOURNAL) of December/22,/2021
- what: The authors explore whether the NADase activity of SARM1 also contributes to developmental signaling. While degenerative and developmental SARM1 signaling share a requirement for NAD+ hydrolysis the authors demonstrate that these signals use distinct upstream and downstream mechanisms. The authors investigate whether activation of dSarm1 for developmental signaling works through the same . . .
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