HIGHLIGHTS
- who: Simon J. Hogg from the Gene Regulation Laboratory, Peter MacCallum Cancer Center, Grattan Street, Melbourne, VIC, Australia have published the article: Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer, in the Journal: (JOURNAL)
- what: This study provides an epigenetic hierarchy for IFNγstimulated gene_expression.
SUMMARY
Pro-inflammatory cytokines directly activate signaling cascades, however, epigenetic mechanisms are also critical for coordinated inflammatory gene_expression. The authors first performed RNA-sequencing (RNA-seq) in AT3 cells treated acutely with recombinant IFNγ or vehicle control . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.