Distinct molecular etiologies of male and female hepatocellular carcinoma

HIGHLIGHTS

• who: Heini M. Natri from the (UNIVERSITY) have published the article: Distinct molecular etiologies of male and female hepatocellular carcinoma, in the Journal: (JOURNAL)
• what: Methods: Here the authors characterize the sex-shared and sex-specific regulatory changes in HCC tumors in the TCGA LIHC cohort using combined and sex-stratified differential expression and eQTL analyses. The authors show that male and female HCC exhibit differences in the dysregulation of genes and germline genetic regulation of tumor gene_expression. This work provides a framework for future studies on sex-biased cancers.
• how: The authors . . .
  

   

  

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