Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific cd8+ t_cells in pancreatic cancer

HIGHLIGHTS

  • who: Adam L. Burrack et al. from the DepartmentUniversity of, Minneapolis, Minnesota, USA have published the article: Distinct myeloid antigen-presenting cells dictate differential fates of tumor-specific CD8+ T_cells in pancreatic cancer, in the Journal: (JOURNAL) of May/19,/2021
  • what: The authors investigate how myeloid subsets differentially shape immunity to pancreatic ductal adenocarcinoma (PDA). The authors show that tumor antigenicity sculpts myeloid cell composition and functionality. The authors investigate the role of myeloid subsets on T_cell priming, differentiation, and antitumor function in PDA mouse models that permit longitudinal analysis of endogenous tumor-specific . . .

     

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