HIGHLIGHTS
- who: Brian E. Hawes from the Fro", : the Howard Hughes Medical Institute, Departments of Medicine (Cardiology) and Biochemistry, Duke University Medical Center, Durham, North Carolina , have published the research work: Distinct Pathways of Gi- and G-mediated Mitogen-activated Protein Kinase Activation (∗), in the Journal: (JOURNAL)
- what: This study compares the mechanisms of MAPK activation employed by Gi- and Gq-coupled receptors using inhibitors of cellular signal_transduction (e_g a Gf3"Y subunit-sequestrant peptide, dominant negative mutants of p21 ras and p74 raf'l, protein-tyrosine kinase inhibitors, and cellular depletion of PKC) in a . . .
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