Distinct ring1b complexes defined by dead-box helicases and emt transcription factors synergistically enhance e-cadherin silencing in breast cancer

HIGHLIGHTS

• who: Yawei Wang from the (UNIVERSITY) have published the Article: Distinct Ring1b complexes defined by DEAD-box helicases and EMT transcription factors synergistically enhance E-cadherin silencing in breast cancer, in the Journal: (JOURNAL)
• what: The authors showed increased expression of Ring1b promoted metastasis by weakening cell-cell adhesions of breast cancer cells. Breast cancer is the second leading cause of cancer death in women, and metastasis is widely accepted as the major reason for cancer mortality1,2.
• how: Western blot data showed that expression of H2AK119ub was Ring1b-dependent in 10 A . . .
  

   

  

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