Distinct roles of classical and lectin pathways of complement in preeclamptic placentae

HIGHLIGHTS

  • who: Beatrice Belmonte from the Brunel University London, United Kingdom have published the paper: Distinct Roles of Classical and Lectin Pathways of Complement in Preeclamptic Placentae, in the Journal: (JOURNAL)
  • what: The data presented in this study show that C is activated in PE placenta through the lectin pathway and that the role of C1q is to promote vascular remodeling in decidua rather than to activate the C classical pathway.

SUMMARY

    Pre-eclampsia (PE) is a serious clinical condition that occurs in 3-5% of pregnant women in the second half . . .

     

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