Distinct sars-cov-2 rna fragments activate toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia

HIGHLIGHTS

• who: Thomas Wallach and colleagues from the University North Carolina at Chapel Hill, United States have published the Article: Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia, in the Journal: (JOURNAL)
• what: Since the authors focused on ssRNA-sensing TLRs in the study , the authors further pruned this data set based on three criteria: (i) high probability to be single-stranded, (ii) low/weak base_pairing potential, and_(iii) best base_pairing target not being in local genomic proximity. To avoid arbitrary probability . . .
  

   

  

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