Distribution patterns of tau pathology in progressive supranuclear palsy

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  • who: Gabor G. Kovacs from the Case cohort This study includes , individuals in banked collection of brains from longitudinally followed subjects at the Center of Neurodegenerative Disease Research (CNDR) Brain Bank at the University of Pennsylvania, Philadelphia, PA and brain banks in Munich, Germany, Barcelona, Spain, London, UK, and Rotterdam, The Netherlands (Table, )Cases for the study were selected based on the presence of globose NFTs in the subthalamic nucleus, substantia nigra, and globus pallidus together with tufted astrocytes in the striatum and eventually in the frontal cortex. Cases were grouped following PSP-RS, PSP-P, PSP . . .

     

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