Disturbance of the warburg effect by dichloroacetate and niclosamide suppresses the growth of different sub-types of malignant pleural mesothelioma in vitro and in vivo

HIGHLIGHTS

  • who: October and colleagues from the Sungkyunkwan University, South Korea Shanghai Jiao Tong University, China have published the research work: Disturbance of the Warburg effect by dichloroacetate and niclosamide suppresses the growth of different sub-types of malignant pleural mesothelioma in vitro and in vivo, in the Journal: (JOURNAL)
  • what: The study protocol was approved by the institutional Animal Ethics Committee (approval reference number: CULATR 5170-19), and standard humane endpoints for animal research were applied (Lam et_al, 2020). The authors show a novel combination of DCA with Nic that synergistically suppressed tumor growth in . . .

     

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