Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level in endothelial cell nuclei

HIGHLIGHTS

• who: Disturbed Flow Enhances Inflammatory et al. from the Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia, United States of, Division of have published the paper: Disturbed Flow Enhances Inflammatory Signaling and Atherogenesis by Increasing Thioredoxin-1 Level in Endothelial Cell Nuclei, in the Journal: PLOS ONE | www.plosone.org of September/29,/2014
• what: The authors examined the role of nuclear Trx1 in atherogenic signaling using mouse and cultured EC models. This study shows that disturbed oscillatory shear stress induces translocation of Trx1 into vascular endothelial cell . . .
  

   

  

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