Disulfiram oxy-derivatives suppress protein retrotranslocation across the er membrane to the cytosol and initiate paraptosis-like cell death

HIGHLIGHTS

• who: Marina Solovieva and colleagues from the Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia have published the article: Disulfiram Oxy-Derivatives Suppress Protein Retrotranslocation across the ER Membrane to the Cytosol and Initiate Paraptosis-like Cell Death, in the Journal: Membranes 2022, 845 of 27/08/2022
• what: The authors attempted to evaluate the cause of ER swelling and initiation of paraptosis-like cell death induced by DSFoxy in human carcinoma cells using a mass spectrometric analysis of ubiquitome. Blocking the deubiquitinase activity can also be one of the main . . .
  

   

  

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