Divergent binding mode for a protozoan brc repeat to rad51

HIGHLIGHTS

• who: Teodors, Pantelejevs and Marko, Hyvu00f6nen from the DepartmentUniversity of have published the paper: Divergent binding mode for a protozoan BRC repeat to RAD51, in the Journal: (JOURNAL) of 23/05/2022
• what: The authors show LiBRC1 is a high-affinity repeat and determine the crystal_structure of its complex with LiRAD51. Using truncation mutagenesis of the LiBRC1 repeat, the authors demonstrate that high affinity binding is maintained in the absence of an LFDE-like motif and suggest compensatory structural features. The model shows that BRC repeat 4 (BRC4) binds the ATPase domain of RAD51 and . . .
  

   

  

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