Divergent roles of cyp26b1 and endogenous retinoic acid in mouse fetal gonads

HIGHLIGHTS

  • who: CYP and collaborators from the Laboratoire de Développement des Gonades, UMR Stabilité Génétique, Cellules Souches et Radiations have published the paper: Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads, in the Journal: Biomolecules 2019, 9, 536 of /2019/
  • what: The authors demonstrate that some effects of RA in mouse fetal gonads are not recapitulated by the invalidation or up-regulation of CYP26B1. The authors develop a gain-of-function model to express CYP26A1 or CYP26B1. The authors report similarly that fetal Sertoli cell proliferation is inhibited by . . .

     

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