HIGHLIGHTS
- who: Stefan Schoenfelder et al. from the Babraham Institute, Cambridge , AT, UKUniversity of have published the research work: Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors investigate the differences in chromosome conformation between the embryonic and extraembryonic lineages, using mouse ESCs and TSCs as models.
- how: To identify interaction differences between TSCs and ESCs in a stringent manner the authors developed a statistical model (see Methods) that performs a direct comparison of the mapped data from both . . .
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