HIGHLIGHTS
- who: Modification from the of Biochemistry, University of Leicester, Leicester, United Kingdom have published the research work: Diverse Functionalization of Aurora-A Kinase at Specified Surface and Buried Sites by Native Chemical Modification, in the Journal: PLOS ONE | www.plosone.org
- what: The authors demonstrate here that one such technique which involves conversion of cysteine to dehydroalanine followed by thiol nucleophile addition is suitable for the sitespecific installation of a wide range of chemical mimics of PTMs including acetylated and dimethylated lysine and other unnatural amino acids. The authors show that chemical of cysteine residues . . .
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