Diverse roles of the exon junction complex factors in the cell cycle, cancer, and neurodevelopmental disorders-potential for therapeutic targeting

HIGHLIGHTS

  • who: Hannah Martin and collaborators from the Department of Biology, Pennsylvania State University, University Park, State College, PA, USA have published the Article: Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting, in the Journal: (JOURNAL)

SUMMARY

    Processing of mRNA is crucially regulated in the mammalian cells via differential alternative splicing, translation, mRNA localization, and NMD. The EJC has emerged as a significant component and regulator of mRNA processing. The EJC is composed of three core components and a peripheral factor, although . . .

     

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