Diving into the evolutionary history of hsc70-linked selective autophagy pathways: endosomal microautophagy and chaperone-mediated autophagy

HIGHLIGHTS

• who: Simon Schnebert and collaborators from the (UNIVERSITY) have published the research: Diving into the Evolutionary History of HSC70-Linked Selective Autophagy Pathways: Endosomal Microautophagy and Chaperone-Mediated Autophagy, in the Journal: Cells 2022, 1945 of /2022/
• what: The data the authors aggregated in the present review provide unequivocal evidence that the LAMP2 gene appeared at the onset of vertebrate radiation , de facto indicating that CMA (as currently described) is specific to this lineage.

SUMMARY

Pioneering studies performed by Fred J Dice using bovine pancreatic ribonuclease A (RNase A) initially identified . . .

 



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