HIGHLIGHTS
- who: TYPE et al. from the Universidade do Porto, Portugal (CSIC), Spain have published the research: DNA accelerates the protease inhibition of a bacterial serpin chloropin, in the Journal: (JOURNAL)
- how: The authors showed that chloropin is an inhibitory serpin and its activity could be regulated by cofactors such as heparin and DNA and DNA is likely a natural cofactor for chloropin.
- future: Clearly further research on prokaryotic serpins is required to address these questions.
SUMMARY
Serine protease inhibitors (Serpins) are the largest and most widely distributed family of . . .
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