Dna barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response

HIGHLIGHTS

  • who: Louise A. Baldwin from the (UNIVERSITY) have published the paper: DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response, in the Journal: (JOURNAL) of 15/02/2021
  • what: The authors show preexisting cell populations are selected for at the primary site, metastases and in the context of immunotherapy. To determine if immune control of tumour growth was driven at a clonal level, the authors examined the number and distribution of barcodes present in primary tumours collected at an ethical endpoint in the experiment described above. The authors identified . . .

     

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