Dna damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint

HIGHLIGHTS

  • who: Josie K. Collins from the for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton , BJ, UK* These authors have published the research work: DNA damage induces a meiotic arrest in mouse oocytes mediated by the spindle assembly checkpoint, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 28/04/2015
  • what: The authors show that DNA damage activates a pathway involving the spindle assembly checkpoint (SAC) in response to chemically induced double strand breaks UVB and ionizing radiation. The authors propose that its essential role in the detection of DNA damage . . .

     

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