HIGHLIGHTS
- who: Gwenneg Kerdivel from the Cochin Institute, CNRS UMR8104, University of Paris, rue du Faubourg Saintu2011Jacques, Paris, France have published the research: DNA hypermethylation driven by, in the Journal: (JOURNAL)
- what: The authors show that in is linked to the increased expression of methylu2011 transferases DNMT1 and DNMT3A driven by a gain of gene copy number and cell hyperproliferation. The authors demonstrate that contributes to tumor aggressiveness by favoring tumor This effect could be at least partially reversed by treatment with the agent Conclusions The authors identified potential molecular drivers of DNA hypermethylation in ACC . . .
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