HIGHLIGHTS
- who: Yunyun An from the (UNIVERSITY) have published the research: DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation, in the Journal: (JOURNAL) of 12/07/2022
- what: Through orientationaware analyses of cfDNA fragmentation patterns against the nucleosome structure and integration with multidimensional functional genomics data, here the authors report a DNA methylation - nuclease preference - cutting end - size distribution axis, demonstrating the role of DNA methylation as a functional molecular regulator of cfDNA fragmentation. Nature Communications | 14:287 To enhance the reliability of the model , in each analysis, multiple datasets from . . .
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