Dna methylation-based patterns for early diagnostic prediction and prognostic evaluation in colorectal cancer patients with high tumor mutation burden

HIGHLIGHTS

  • who: Hao Huang and colleagues from the Second Military Medical University, China have published the Article: DNA methylation-based patterns for early diagnostic prediction and prognostic evaluation in colorectal cancer patients with high tumor mutation burden, in the Journal: (JOURNAL)
  • what: The authors integrated DNA methylation profiling and tumor mutation data to investigate the direct correlation of DNA methylation with TMB and to discover and better understand novel early diagnostic and prognostic biomarkers for ICI therapies in CRC. The study was ethically approved by the Institutional Ethics Committee of Harbin Medical University and written informed . . .

     

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