Dna methylation of patatin-like phospholipase domain-containing protein 6 gene contributes to the risk of intracranial aneurysm in males

HIGHLIGHTS

  • who: Jie Sun from the Department of Neurosurgery, Ningbo First Hospital, Ningbo, China, Key Laboratory of Precision Medicine for Capital Medical University, China have published the paper: DNA Methylation of Patatin-Like Phospholipase Domain-Containing Protein 6 Gene Contributes to the Risk of Intracranial Aneurysm in Males, in the Journal: (JOURNAL)
  • what: The authors aimed to test the association between PNPLA6 DNA methylation and IA in Han Chinese individuals. In the present study, the cell experiments showed that DNA methylase inhibitor significantly upregulated PNPLA6 transcription levels in the HPCASMC, which suggested that DNA methylation may . . .

     

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