HIGHLIGHTS
- who: Dennis Niebel from the Department of Otorhinolaryngology, University Medical Center Bonn (UKB), Venusbergu2011Campus, Bonn, Germany have published the research work: DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy, in the Journal: (JOURNAL)
- what: The authors comprehensively analyzed TIGIT methylation in melanoma with regard to transcriptional activity, immune cell infiltrates, an IFN-u03b3 signature, markers of T_cell activation, patients` prognosis, and response to immunotherapy. The authors investigated a potential epigenetic regulation of TIGIT expression via DNA . . .
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