HIGHLIGHTS
- who: Geoffrey Casas et al. from the CNRS with the University of France have published the Article: DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer, in the Journal: (JOURNAL) of 29/09/2022
- what: The authors show that formulated STAT3 MCs enabled specific STAT3 targeting that resulted in proliferation inhibition, apoptosis induction, slowing of cell cycle progression, and a decrease in STAT3 target gene_expression. The authors provide the first demonstration of the therapeutic potential of short DNA MCs as a new type of decoy for TF inhibition . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.