HIGHLIGHTS
- who: DNA double-strand breaks and collaborators from the Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, USA and , Repair have published the article: DNA-PK -dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks, in the Journal: (JOURNAL) of November/24,/2021
- what: The authors report that RECQL4 stabilizes the NHEJ machinery at DSBs to promote repair. These results are supported by the experiments showing that accumulation of the NHEJ factors, DNA-PKcs, Ku70, LIG4, XRCC4 and XLF to the chromatin fraction following DNA damage . . .
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